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Appendix

Physician-reviewed medical opinions and prescriptions for AI agents.

Links

README

From the repo.

Appendix MCP Server

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.

Installation

Claude Code

claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Claude Desktop / Claude Web Connectors

Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:

{
  "mcpServers": {
    "appendix": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

Other clients

ClientURL
Claude Code, Claude Desktop, Claude.ai connectorshttps://mcp.appendix.com/mcp
Anthropic Messages API (mcp_servers)https://mcp.appendix.com/mcp

The server speaks Streamable HTTP only — the current MCP spec transport (2025-03-26).

Available Tools

ToolDescription
search_knowledge_baseSearch medical literature and treatment guidelines
submit_encounterSubmit a clinical letter for physician review
list_conditionsList available conditions and medications

Development

npm install
npm run build
npm start

Watch mode:

npm run dev

Environment Variables

VariableDefaultDescription
API_BASE_URLhttps://api.appendix.comAppendix API base URL
PORT3001HTTP listener port

Endpoints

MethodPathPurpose
GET/healthHealth probe for the hosting platform
POST GET DELETE/mcpStreamable HTTP transport (stateless mode)

Config for your environment

Use the endpoint URL below in your config. No API key — you connect directly.

Tool

OS

Config file: ~/.cursor/mcp.json

{
  "mcpServers": {
    "mcp-server": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

Paste into mcpServers in the config file. Restart Cursor after saving.

If this MCP is also published on mcpchannel.ai, you can subscribe from Browse and use the gateway config there instead.